{"id":4240,"date":"2024-09-27T16:14:35","date_gmt":"2024-09-27T08:14:35","guid":{"rendered":"\/\/www.tradeda.com\/?p=4240"},"modified":"2024-09-27T16:14:35","modified_gmt":"2024-09-27T08:14:35","slug":"%e6%9c%89%e6%9c%ba%e9%93%9c%e8%af%95%e5%89%82-organocuprate","status":"publish","type":"post","link":"\/\/www.tradeda.com\/archives\/4240","title":{"rendered":"\u6709\u673a\u94dc\u8bd5\u5242 Organocuprate"},"content":{"rendered":"<p><a href=\"\/\/www.tradeda.com\/\"><strong>\u6709\u673a\u94dc\u8bd5\u5242 Organocuprate<\/strong><\/a><\/p>\n<p>\u94dc\u7684\u6709\u673a\u5316\u5408\u7269\u4f5c\u4e3a\u6709\u673a\u5408\u6210\u4e2d\u7684\u91cd\u8981\u8bd5\u5242\u662f20\u4e16\u7eaa60\u5e74\u4ee3\u540e\u671f\u53d1\u5c55\u8d77\u6765\u7684\u3002\u5b83\u5305\u62ec\u6709\u673a\u94dc\u53ca\u6709\u673a\u94dc\u9502\u4e24\u7c7b\u5316\u5408\u7269\u3002\u6709\u673a\u94dc\u9502\u8bd5\u5242\u4e00\u822c\u8868\u793a\u4e3aR2CuLi\uff0c\u8fd9\u4e9b\u8bd5\u5242\u6bd4\u8457\u540d\u7684\u6709\u673a\u94dc\uff08\u2160\uff09\u8bd5\u5242\u66f4\u7a33\u5b9a\uff0c\u800c\u4e14\u66f4\u6d3b\u6cfc\u3002R2CuLi\u662f\u4e00\u79cd\u53cc\u91d1\u5c5e\u7edc\u5408\u7269\uff0c\u7531\u4e8e\u5b83\u7684\u6eb6\u89e3\u6027\u597d\uff0c\u6d3b\u6027\u597d\uff0c\u56e0\u6b64\u662f\u6709\u673a\u94dc\u8bd5\u5242\u5728\u6709\u673a\u5408\u6210\u4e0a\u5e38\u7528\u7684\u6709\u673a\u5408\u6210\u8bd5\u5242\u3002\u6709\u673a\u916e\u9502\u8bd5\u5242\u6709\u7528\u7684\u53cd\u5e94\u4e4b\u4e00\u662f\u5b83\u4eec\u5bf9\u4e0d\u9971\u548c\u916e\u8fdb\u884c\u5171\u8f6d\u52a0\u6210\uff0c\u800c\u5728\u8fd9\u4e9b\u6761\u4ef6\u4e0b\uff0c\u975e\u5171\u8f6d\u916e\u7684\u7fb0\u57fa\u5e76\u4e0d\u53d1\u751f\u53cd\u5e94\u3002<\/p>\n<p><img decoding=\"async\" class=\"alignnone size-full wp-image-4241\" src=\"\/\/www.tradeda.com\/wp-content\/uploads\/2024\/09\/1723362027486-3.png\" width=\"651\" height=\"384\" srcset=\"\/\/www.tradeda.com\/wp-content\/uploads\/2024\/09\/1723362027486-3.png 651w, \/\/www.tradeda.com\/wp-content\/uploads\/2024\/09\/1723362027486-3-300x177.png 300w\" sizes=\"(max-width: 651px) 100vw, 651px\" \/><\/p>\n<p>\u8be5\u8bd5\u5242\u53cd\u5e94\u6027\u975e\u5e38\u9ad8\u3001\u5bf9\u4e8e\u7acb\u4f53\u4f4d\u963b\u5927\u7684\u78b3\u539f\u5b50\u4e5f\u53ef\u4ee5\u53cd\u5e94\u3002\u901a\u8fc7TMSCl\u7b49\u786c\u8def\u6613\u65af\u9178\uff0c\u53ef\u4ee5\u52a0\u901f1,4-\u52a0\u6210\u53cd\u5e94\u3002<\/p>\n<p>\u9664\u4e86\u4e0e\u6709\u673a\u9502\u8bd5\u5242\u4ee5\u5916\uff0c\u4e5f\u53ef\u4ee5\u4e0e\u683c\u5229\u96c5\u8bd5\u5242\u3001\u6709\u673a\u950c\u8bd5\u5242\u7b49\u4e00\u8d77\u4f7f\u7528\u3002\u7279\u522b\u662f\u548c\u540e\u4e24\u8005\u7ed3\u5408\u4f7f\u7528\u65f6\uff0c\u53ef\u4ee5\u5c06\u94dc\u8bd5\u5242\u7684\u91cf\u51cf\u5c0f\u5230\u50ac\u5316\u5242\u91cf\u3002<\/p>\n<p>\u4e24\u5f53\u91cf\u7684\u6709\u673a\u9502\u8bd5\u5242\u5bf9\u4e8e\u53cd\u5e94\u7684\u987a\u5229\u8fdb\u884c\u5f88\u5fc5\u8981\uff0c\u5b9e\u9645\u4ec5\u6709\u4e00\u5f53\u91cf\u5728\u53cd\u5e94\u4e2d\u6d88\u8017\u3002\u901a\u8fc7\u5bfc\u5165\u8f83\u96be\u8fc1\u79fb\u7684\u914d\u4f53\uff08dummy ligand\uff09\u751f\u6210\u6742\u6709\u673a\u94dc\u8bd5\u5242 (mixed organocuprate)[R(X)CuLi](X = alkenyl, -CN, -SR\u2019,-NR\u20192, PR\u20192 etc.)\u3001\u53ef\u4ee5\u5bf9\u91cd\u8981\u7684\u53cd\u5e94\u5242\u9ad8\u6548\u5229\u7528\u3002<\/p>\n<p><img decoding=\"async\" class=\"alignnone size-full wp-image-4242\" src=\"\/\/www.tradeda.com\/wp-content\/uploads\/2024\/09\/1706789231115-8.jpg\" width=\"557\" height=\"412\" srcset=\"\/\/www.tradeda.com\/wp-content\/uploads\/2024\/09\/1706789231115-8.jpg 557w, \/\/www.tradeda.com\/wp-content\/uploads\/2024\/09\/1706789231115-8-300x222.jpg 300w\" sizes=\"(max-width: 557px) 100vw, 557px\" \/><\/p>\n<p>\u8fd1\u5e74\u6765\uff0c\u901a\u8fc7\u50ac\u5316\u5242\u91cf\u7684\u94dc-\u624b\u6027\u81a6\u914d\u4f53\u7684\u4f7f\u7528\uff0c\u53d1\u5c55\u4e86\u8bb8\u591a\u4e0d\u5bf9\u79f01,4-\u52a0\u6210\u53cd\u5e94\u3002\u6291\u83cc\u65b9\u9762\u4ece\u4e0a\u56fe\u7684\u7ed3\u679c\u53ef\u4ee5\u770b\u51fa\uff0c\u5728\u4e00\u5b9a\u7684\u6d53\u5ea6\u4e0b\u9175\u6bcd\u83cc\/\u950c\u53d1\u9175\u4ea7\u7269\u5bf9\u75e4\u75ae\u4e19\u9178\u6746\u83cc\u53ef\u4ee5\u53d1\u6325\u4e00\u5b9a\u7684\u6291\u5236\u4f5c\u7528\u3002<\/p>\n<p>\u9488\u5bf9\u9752\u6625\u671f\u7684\u75e4\u75ae\u4ee5\u53ca\u5934\u76ae\u95ee\u9898\uff0c\u9175\u6bcd\u83cc\u950c\u53d1\u9175\u4ea7\u7269\u90fd\u53ef\u4ee5\u53d1\u6325\u5b83\u72ec\u6709\u7684\u7efc\u5408\u529f\u6548\u3002\u968f\u7740\u6c14\u6e29\u7684\u5347\u9ad8\uff0c\u590f\u5929\u7684\u5230\u6765\u76ae\u80a4\u4e2d\u76ae\u8d28\u5206\u6ccc\u589e\u591a\uff0c\u55dc\u6cb9\u7c7b\u771f\u83cc\u8fc7\u5ea6\u589e\u6b96\u8fdb\u4e00\u6b65\u5bfc\u81f4\u76ae\u80a4\u83cc\u7fa4\u5931\u8861\uff0c\u8fdb\u800c\u9020\u6210\u7619\u75d2\u3001\u89d2\u8d28\u5c42\u7ec6\u80de\u589e\u751f\u3001\u5f02\u5e38\u7b49\u95ee\u9898\u3002\u76ae\u80a4\u7684\u523a\u6fc0\u7619\u75d2\u8bf1\u5bfc\u6293\u6320\u53ca\u8fc7\u5ea6\u6e05\u6d01\uff0c\u5f15\u53d1\u708e\u75c7\u53cd\u5e94\uff0c\u52a0\u901f\u89d2\u8d28\u7ec6\u80de\u5f02\u5e38\u5206\u5316\uff0c\u8fdb\u800c\u7834\u574f\u4e86\u76ae\u80a4\u5c4f\u969c\u3002\u540e\u671f\u73af\u5883\u5916\u6765\u7269\u7684\u523a\u6fc0\u589e\u52a0\u4f1a\u8fdb\u4e00\u6b65\u5bfc\u81f4\u76ae\u80a4\u5fae\u751f\u6001\u7684\u5931\u8861\u3002<\/p>\n<p><img decoding=\"async\" class=\"alignnone size-full wp-image-4243\" src=\"\/\/www.tradeda.com\/wp-content\/uploads\/2024\/09\/1710429824961-1.jpg\" width=\"525\" height=\"350\" srcset=\"\/\/www.tradeda.com\/wp-content\/uploads\/2024\/09\/1710429824961-1.jpg 525w, \/\/www.tradeda.com\/wp-content\/uploads\/2024\/09\/1710429824961-1-300x200.jpg 300w\" sizes=\"(max-width: 525px) 100vw, 525px\" \/><\/p>\n<p>\u68b3\u7406\u9175\u6bcd\u83cc\/\u950c\u53d1\u9175\u4ea7\u7269\u7684\u529f\u6548\u7279\u70b9\uff1a<\/p>\n<p>\u9996\u5148\uff0c\u950c\u7684\u4f5c\u7528\u5c31\u5728\u4e8e\u901a\u8fc7\u5916\u7528\u6216\u8005\u53e3\u670d\u5728\u4e00\u5b9a\u7a0b\u5ea6\u4e0a\u8c03\u8282\u6cb9\u8102\u4ee3\u8c22\uff0c\u51cf\u5c11\u6cb9\u8102\u7684\u8fc7\u5ea6\u5206\u6ccc\uff0c\u8fdb\u800c\u6291\u5236\u771f\u83cc\u751f\u957f\uff0c\u8c03\u8282\u83cc\u7fa4\u5e73\u8861\uff1b\u540c\u65f6\uff0c\u950c\u5143\u7d20\u8fd8\u53ef\u4ee5\u4fc3\u8fdb\u7ec6\u80de\u5206\u88c2\uff0c\u4fc3\u8fdb\u76ae\u80a4\u7684\u6108\u5408\uff1b\u53e6\u5916\uff0c\u950c\u8fd8\u53ef\u4ee5\u8c03\u8282\u76ae\u80a4\u7ec6\u80de\u4e2d\u7684\u514d\u75ab\u5e94\u7b54\uff0c\u63d0\u9ad8\u76ae\u80a4\u7684\u514d\u75ab\u5e73\u8861\uff0c\u6062\u590d\u76ae\u80a4\u5c4f\u969c\u529f\u80fd\u3002<\/p>\n<p>\u968f\u7740\u5e02\u573a\u5bf9\u5b89\u5168\u3001\u5065\u5eb7\u3001\u9ad8\u6548\u8bc9\u6c42\u7684\u4e0d\u65ad\u63d0\u9ad8\uff0c\u5986\u98df\u540c\u6e90\u7684\u9175\u6bcd\u83cc\/\u950c\u53d1\u9175\u4ea7\u7269\u56e0\u4e3a\u5176\u5728\u98df\u54c1\u9886\u57df\u7684\u5e7f\u6cdb\u4f7f\u7528\uff0c\u6709\u673a\u5f62\u5f0f\u3001\u5b89\u5168\u3001\u751f\u7269\u5229\u7528\u5ea6\u9ad8\uff0c\u4ee5\u53ca\u5728\u4fee\u590d\u3001\u63a7\u6cb9\u3001\u6291\u83cc\u7b49\u529f\u6548\u9886\u57df\u7684\u6df1\u5165\u7814\u7a76\uff0c\u672a\u6765\u5e94\u7528\u524d\u666f\u53ef\u671f\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u6709\u673a\u94dc\u8bd5\u5242 Organocuprate \u94dc\u7684\u6709\u673a\u5316\u5408\u7269\u4f5c\u4e3a\u6709\u673a\u5408\u6210\u4e2d\u7684\u91cd\u8981\u8bd5\u5242\u662f20\u4e16\u7eaa60\u5e74\u4ee3\u540e\u671f\u53d1\u5c55\u8d77\u6765\u7684\u3002\u5b83\u5305\u62ec\u6709\u673a\u94dc\u53ca\u6709\u673a\u94dc\u9502\u4e24\u7c7b\u5316&#8230; <\/p>\n","protected":false},"author":2,"featured_media":4241,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[],"class_list":["post-4240","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news"],"_links":{"self":[{"href":"\/\/www.tradeda.com\/wp-json\/wp\/v2\/posts\/4240","targetHints":{"allow":["GET"]}}],"collection":[{"href":"\/\/www.tradeda.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"\/\/www.tradeda.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"\/\/www.tradeda.com\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"\/\/www.tradeda.com\/wp-json\/wp\/v2\/comments?post=4240"}],"version-history":[{"count":1,"href":"\/\/www.tradeda.com\/wp-json\/wp\/v2\/posts\/4240\/revisions"}],"predecessor-version":[{"id":4244,"href":"\/\/www.tradeda.com\/wp-json\/wp\/v2\/posts\/4240\/revisions\/4244"}],"wp:featuredmedia":[{"embeddable":true,"href":"\/\/www.tradeda.com\/wp-json\/wp\/v2\/media\/4241"}],"wp:attachment":[{"href":"\/\/www.tradeda.com\/wp-json\/wp\/v2\/media?parent=4240"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"\/\/www.tradeda.com\/wp-json\/wp\/v2\/categories?post=4240"},{"taxonomy":"post_tag","embeddable":true,"href":"\/\/www.tradeda.com\/wp-json\/wp\/v2\/tags?post=4240"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}